基本信息

姓名：左永春

职称：教授(三级)

导师：博士生导师

联系方式：yczuo@imu.edu.cn

课题组网站：http://bioinfor.imu.edu.cn/

教育与工作经历

2017.12 - 至今 生命科学学院、教授、博士生导师

2014.12 – 2017.11 生命科学学院、副教授

2011.07 – 2014.11 生命科学学院、讲师

2006.09 – 2011.06 内蒙古大学物理科学与技术学院、硕博连读

研究方向

主要利用生物信息学和计算生物学方法，围绕哺乳动物发育编程与体细胞重编程相关的数字胚胎、关键核酸/蛋白质等调控因子的计算生物学、数字健康与精准医学相关的人工智能建模等方面展开研究。

表彰奖励

曾获国家青年拔尖人才（2022），内蒙古自治区杰出青年基金（2017），内蒙古自治区“草原英才”（2019，2021滚动），内蒙古自治区 “新世纪321人才工程” （2019，2021滚动）；内蒙古自治区高等学校“青年科技英才”（2018）；全国大学生生命科学创新创业大赛指导教师二等奖（2019）；内蒙古大学“三全育人”先进个人（2019）；内蒙古自治区优秀博士学位论文（2014）；国家宝钢特等奖（2010）等。

学术（社会）兼职

担任Current Gene Therapy期刊编委，Frontiers多个期刊的客座/助理编辑，中国生物信息学会表观遗传信息学专委会秘书长、中国细胞生物学学会专委会委员、中国计算机学会高级会员、内蒙古健康数字学会秘书长、内蒙古生物物理与生物信息学会副秘书长等。

近5年代表性论文

1.Lei Zheng, Pengfei Liang, Chunshen Long, Haicheng Li, Hanshuang Li, Yuchao Liang, Xiang He, Qilemuge Xi, Yongqiang Xing* and Yongchun Zuo*, EmAtlas: a comprehensive atlas for exploring spatiotemporal activation in mammalian embryogenesis. Nucleic Acids Research, 2023, 51(D1), D924–D932 (2021 IF: 19.160).

2.Hanshuang Li, Chunshen Long, Yan Hong, Liaofu Luo*, Yongchun Zuo*, Characterizing Cellular Differentiation Potency and Waddington Landscape via Energy Indicator, Research, 2023, 6: 0118 (2021 IF: 11.036).

3.Hao Wang, Zhaoyue Zhang, Haicheng Li, Jinzhao Li, Hanshuang Li, Mingzhu Liu, Pengfei Liang, Qilemuge Xi, Yongqiang Xing*, Lei Yang*, Yongchun Zuo*, A cost-effective machine learning-based method for preeclampsia risk assessment and driver genes discovery. Cell & Bioscience, 2023, 13:41 (2021 IF: 9.584).

4.Jinzhao Li, Xiang He, Shuang Gao, Yuchao Liang, Zhi Qi, Qilemuge Xi, Yongchun Zuo*, Yongqiang Xing*, The Metal-binding Protein Atlas (MbPA): an integrated database for curating metalloproteins in all aspects, Journal of Molecular Biology, 2023 168117. (2021 IF: 6.151).

5.Mingzhu Liu, Jian Zhou, Qilemuge Xi, Yuchao Liang, Haicheng Li, Pengfei Liang, Yuting Guo, Ming Liu, Temuqile Temuqile, Lei Yang*, Yongchun Zuo*, A computational framework of routine test data for the cost-effective chronic disease prediction, Briefings in Bioinformatics, 2023, 23: bbad054 (2021 IF: 13.994).

6.Lei Zheng, Dongyang Liu, Yuan Alex Li, Siqi Yang, Yuchao Liang, Yongqiang Xing* and Yongchun Zuo*, RaacFold: a webserver for 3D visualization and analysis of protein structure by using reduced amino acid alphabets. Nucleic Acids Research, 2022, 50(W1), W633-W638 (2021 IF: 19.160).

7.Yu Sun, Haicheng Li, Lei Zheng, Jinzhao Li, Yan Hong, Pengfei Liang, Lai-Yu Kwok, Yongchun Zuo*, Wenyi Zhang*, Heping Zhang*, iProbiotics: a machine learning platform for rapid identification of probiotic properties from whole-genome primary sequences. Briefings in Bioinformatics, 2022, 23(1) bbab477 (2021 IF: 13.994).

8.Lemuge Chao, Siqi Yang, Hanshuang Li, Chunshen Long, Qilemuge Xi, Yongchun Zuo*. Competitive binding of TET1 and DNMT3A/B cooperates the DNA methylation pattern in human embryonic stem cells, BBA - Gene Regulatory Mechanisms, 2022, 1865 (7) 194861. (2021 IF:6.304)

9.Baofang Xu, Dongyang Liu, Zerong Wang, Ruixia Tian, Yongchun Zuo*, Multi-substrate Selectivity Based on Key Loops and Non-homologous Domains: New Insight into ALKBH Family, Cellular and Molecular Life Sciences, 2021, 78(1):129-141 (2020 IF: 9.261).

10.Shiyuan Wang, Qi Zhang, Chunlu Yu, Yiyin Cao, Yongchun Zuo*, Lei Yang*, Immune cell infiltration based signature for prognosis and immunogenomic analysis in breast cancer, Briefings in Bioinformatics, 2021, 22(2):2020-2031. (2020 IF: 11.622) ESI 1%高被引论文.

11.Hao Wang, Pengfei Liang, Lei Zheng, ChunShen Long, HanShuang Li, Yongchun Zuo*, eHSCPr discriminating the cell identity involved in endothelial to hematopoietic transition. Bioinformatics, 2021 37(15) 2157–2164. (2020 IF: 6.937).

12.Lei Zheng, Dongyang Liu, Wuritu Yang, Lei Yang*, Yongchun Zuo*,  RaacLogo: a new sequence logo generator by using reduced amino acid clusters, Briefings in Bioinformatics, 2021, 22(3):bbaa096 (2020 IF: 11.622) ESI 1%高被引论文.

13.Chunshen Long, Wei Li, Pengfei Liang, Shuai Liu, Yongchun Zuo*, Transcriptome Comparisons of Multi-species Identify Differential Genome Activation of Mammals Embryogenesis. 2019, IEEE Access, 2019, 7:7794-7802. (2018 IF: 4.098) ESI 1%高被引论文.

14.Dongyang Liu, Guangpeng Li*, Yongchun, Zuo*, Function determinants of TET proteins: the arrangements of sequence motifs with specific codes. Briefings in Bioinformatics. 2019, 20 (5), 1826-1835. (2018 IF: 9.101) ESI 1%高被引论文.

15.Guangqi Gao Meng Xu Chunling Bai Yulan Yang Guangpeng Li Junyang Xu Zhuying Wei Jiumeng Min Guanghua Su Xianqiang Zhou Jun Guo Yu Hao Guiping Zhang Xukui Yang Xiaomin Xu Randall B Widelitz Cheng-Ming Chuong Chi Zhang Jun Yin* Yongchun Zuo*, Comparative genomics and transcriptomics of Chrysolophus provide insights into the evolution of complex plumage colouration. GigaScience, 2018, 7(10) 1-14. (2017 IF: 7.267).

16.Yongchun Zuo*, Yuan Li, Yingli Chen, Guangpeng Li, Zhenhe Yan, Lei Yang. PseKRAAC: A flexible web server for generating pseudo K-tuple reduced amino acids composition. Bioinformatics. 2017, 33(1):122-124 (2016 IF:7.307).ESI 1%高被引论文.