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基本信息
姓名:陈福泉
职称:研究员
电子邮箱:nkufuquanchen@nankai.edu.cn
教育经历
2020/06,南开大学,微生物与生化药学,博士
2016/06,南开大学,微生物与生化药学,硕士
2012/06,聊城大学,生物工程,学士
工作经历
2020/06-2023/06,南开大学生命科学学院,助理研究员
2023/08-至今,内蒙古大学生物医学研究院,研究员
研究方向
干细胞生物学与发育, 转座子与表观遗传调控研究, 染色质高级结构与细胞命运决定
代表性论文
代表性论文(#共同一作,*共同通讯):
1. Fuquan Chen#; Weiyu Zhang#; Dan Xie#; Tingting Gao; Zhiqiang Dong; Xinyi Lu*; Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters, Nucleic Acids Research, 2020, 48(18): 10211-10225.
2. Weiyu Zhang#; Fuquan Chen#; Ruiqing Chen#; Dan Xie; Jiao Yang; Xin Zhao; Renpeng Guo; Yongwang Zhang; Yang Shen; Jonathan Göke; Lin Liu*; Xinyi Lu*; Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes, Nucleic Acids Research, 2019, 47(16): 8485-8501.
3. Fuquan Chen#; Xiaomin Li#; Xiao Feng; Tingting Gao; Weiyu Zhang; Zhi Cheng; Xuan Zhao; Ruiqing Chen; Xinyi Lu*; Long Noncoding RNA Lx8-SINE B2 Interacts with Eno1 to Regulate Self-Renewal and Metabolism of Embryonic Stem Cells, Stem Cells, 2022, 40(12): 1094-1106.
4. Fuquan Chen; Miao Zhang; Xiao Feng; Xiaomin Li; Haotian Sun; Xinyi Lu*; Discovery of a Novel Long Noncoding RNA Lx8-SINE B2 as a Marker of Pluripotency, Stem Cells International, 2021,2021: 1-10.
5. Fuquan Chen; Jiaojiao Ji; Jian Shen; Xinyi Lu*. When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells. Stem Cells International, 2017, 2017(2017): 3250624.
6. Xin Zhao#; Xiaomin Li#; Haiyang Sun#; Xuan Zhao; Tingting Gao; Panpan Shi; Fuquan Chen; Lin Liu; Xinyi Lu*; Dot1l cooperates with Npm1 to repress endogenous retrovirus MERVL in embryonic stem cells, Nucleic Acids Research, 2023.
7. Jinfang Bi#; Wenbin Wang#; Meng Zhang; Baoying Zhang; Man Liu; Guangsong Su; Fuquan Chen; Bohan Chen; Tengfei Shi; Yaoqiang Zheng; Xueyuan Zhao; Zhongfang Zhao; Jiandang Shi; Peng Li; Lei Zhang*; Wange Lu*; KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure, Nucleic Acids Research, 2022, 5(21): 12235-12250.
8. Yuan Wang; Fuquan Chen; Man Zhao; Zhe Yang; Jiong Li; Shuqin Zhang; Weiying Zhang; Lihong Ye*; Xiaodong Zhang*; The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186, Journal of Biological Chemistry, 2017, 292(37): 15395-15407.
9. Yuan Wang; Fuquan Chen; Zhe Yang; Man Zhao; Shuqin Zhang; Yuen Gao; Jinyan Feng; Guang Yang; Weiying Zhang; Lihong Ye*; Xiaodong Zhang*; The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2, Scientific Reports, 2017, 7(1):2070-2070.