基本信息

姓名：陈福泉

职称：研究员

电子邮箱：nkufuquanchen@nankai.edu.cn 

教育经历

2020/06，南开大学，微生物与生化药学，博士

2016/06，南开大学，微生物与生化药学，硕士

2012/06，聊城大学，生物工程，学士

工作经历

2020/06-2023/06，南开大学生命科学学院，助理研究员

2023/08-至今，内蒙古大学生物医学研究院，研究员

研究方向

干细胞生物学与发育, 转座子与表观遗传调控研究, 染色质高级结构与细胞命运决定

代表性论文

代表性论文（#共同一作，*共同通讯）：

1. Fuquan Chen^#; Weiyu Zhang^#; Dan Xie^#; Tingting Gao; Zhiqiang Dong; Xinyi Lu*; Histone chaperone FACT represses retrotransposon MERVL and MERVL-derived cryptic promoters, Nucleic Acids Research, 2020, 48(18): 10211-10225.

2. Weiyu Zhang^#; Fuquan Chen^#; Ruiqing Chen^#; Dan Xie; Jiao Yang; Xin Zhao; Renpeng Guo; Yongwang Zhang; Yang Shen; Jonathan Göke; Lin Liu*; Xinyi Lu*; Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes, Nucleic Acids Research, 2019, 47(16): 8485-8501.

3. Fuquan Chen^#; Xiaomin Li^#; Xiao Feng; Tingting Gao; Weiyu Zhang; Zhi Cheng; Xuan Zhao; Ruiqing Chen; Xinyi Lu*; Long Noncoding RNA Lx8-SINE B2 Interacts with Eno1 to Regulate Self-Renewal and Metabolism of Embryonic Stem Cells, Stem Cells, 2022, 40(12): 1094-1106.

4. Fuquan Chen; Miao Zhang; Xiao Feng; Xiaomin Li; Haotian Sun; Xinyi Lu*; Discovery of a Novel Long Noncoding RNA Lx8-SINE B2 as a Marker of Pluripotency, Stem Cells International, 2021,2021: 1-10.

5. Fuquan Chen; Jiaojiao Ji; Jian Shen; Xinyi Lu*. When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells. Stem Cells International, 2017, 2017(2017): 3250624.

6. Xin Zhao^#; Xiaomin Li^#; Haiyang Sun^#; Xuan Zhao; Tingting Gao; Panpan Shi; Fuquan Chen; Lin Liu; Xinyi Lu*; Dot1l cooperates with Npm1 to repress endogenous retrovirus MERVL in embryonic stem cells, Nucleic Acids Research, 2023.

7. Jinfang Bi^#; Wenbin Wang^#; Meng Zhang; Baoying Zhang; Man Liu; Guangsong Su; Fuquan Chen; Bohan Chen; Tengfei Shi; Yaoqiang Zheng; Xueyuan Zhao; Zhongfang Zhao; Jiandang Shi; Peng Li; Lei Zhang*; Wange Lu*; KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure, Nucleic Acids Research, 2022, 5(21): 12235-12250.

8. Yuan Wang; Fuquan Chen; Man Zhao; Zhe Yang; Jiong Li; Shuqin Zhang; Weiying Zhang; Lihong Ye*; Xiaodong Zhang*; The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186, Journal of Biological Chemistry, 2017, 292(37): 15395-15407.

9. Yuan Wang; Fuquan Chen; Zhe Yang; Man Zhao; Shuqin Zhang; Yuen Gao; Jinyan Feng; Guang Yang; Weiying Zhang; Lihong Ye*; Xiaodong Zhang*; The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2, Scientific Reports, 2017, 7(1):2070-2070.